Kosan Biosciences, Inc. has established a worldwide license agreement with Pfizer for its motilin agonist program. The agreement includes Kosan’s clinical candidate, KOS-2187 and related compounds. KOS-2187 has demonstrated improved gastric emptying in preclinical studies and may have therapeutic benefit in gastrointestinal diseases such as gastro- esophageal reflux disease (GERD), or diabetic gastroparesis (delayed gastric emptying). Under the terms of the license agreement, the two ...